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We are looking into a few options for application lockout on ET1. There are some possible alternatives by developing an native Android application that intercepts the Home button handling, but I don't think this is what you are looking for.
We are working on a user lock out option as part of the Motorola Enterprise Android effort. This would not disable the Home key as such, but will provide a replacement Home screen restricting the user to authorised apps only. This isn't part of RhoElements though so I don't have any more details but you should be able to follow up with the ET1 product team.